South Africa

Lead institution(s)

  • Stellenbosch University
  • University of Cape Town

Lead investigator(s)

  • Grant Theron PhD, MSc
  • Heather Zar, MD, PhD

Staff

  • Zaida Palmer, Presumptive TB Cohort Study Coordinator and Senior Technical Officer
  • Charissa Naidoo, DR-TB Cohort Study Coordinator
  • Brigitta Derendinger, DR-TB Assistant Coordinator of Shipments
  • Raeesa Hussan, DR-TB Cohort Assistant Project Coordinator
  • Megan Hendrikse, Laboratory Manager
  • Dawn Davis, Research Nurse
  • Jane Fortuin, Research Nurse
  • Charlotte Lawn, Research Nurse
  • Zinthle Ntwana, Community Health Worker
  • Fikiswa Seti, Community Health Worker
  • Dandelene Sylvester, Community Health Worker
  • Charmaine van der Walt, Research Nurse
  • As of April 2024

Cohort enrollment capacity

  • Adults with presumptive TB
  • Children with presumptive TB
  • People living with HIV
  • Drug-resistant TB
Estimates of TB burden, 2022
Number Rate per 100,000 population
Total TB incidence 280,000 (182,000 – 398,000) 468 (304 – 665)
HIV-positive TB incidence 152,000 (99,000 – 217,000) 255 (166 – 362)
MDR/RR-TB incidence 11,000 (6,700 – 16,000) 19 (11 – 26)
HIV-negative TB mortality 23,000 (22,000 – 24,000) 39 (37 – 41)
HIV-positive TB mortality 31,000 (9,900 – 64,000) 52 (17 – 107)

Full WHO TB country profile